Why does LSD make you trip?

Justice (@indigodreaming) 7 years, 2 months ago

This is a theory that came to mr that I’m working on that could be completely flawed due to ignorance is basic chemistry/biology. Please point out any and all errors: I have read in a few places, particularly in a book called Escaping the Self, about what oxygen deprivation or changing your oxygen levels can do to your brain. It is said that breathing a certain way (meditation, yoga, I think smoking, too) increase the carbon levels in your brain and lower the oxygen levels, if only slightly. This allows you to reach a meditative state, inner peace, have mild hallucinations, and possibly out of body experiences or OBEs. So following this logic, changing the oxygen/carbon levels in your brain can cause you to have hallucinations. Now the chemical composition of lysergic acid diethylamide (LSD) is C20H25N3O. Which is like 20 units carbon to one unit oxygen. Following the previous logic, could this be way acid makes you hallucinate?

June 9, 2015 at 2:35 pm
Viner Cent (50) (@Viner-Cent) 7 years, 2 months ago ago

The way LSD works, is that it docks to these receptors: 5-HT2A-Receptor, 5-HT-Receptores, Dopamin-and the Adrenoceptores. These cause these effects: http://en.wikipedia.org/wiki/Lysergic_acid_diethylamide#Effects

Source: German Wikipedia Artikel, the English one does not mention all receptors: http://de.wikipedia.org/wiki/LSD#Wirkung_beim_Menschen

Bryan (104) (@Substratum) 7 years, 2 months ago ago

If carbon could make you trip then everyone would be eating a lot of burnt toast. It isn’t carbon, it’s carbon dioxide that has an unhealthy effect on your brain which alters consciousness in the same way that suffocation would lead to unconsciousness and eventually death. There is no similarity between the effects of LSD and the effect of breathing in a way that deprives your brain of the oxygen it needs or traps the waste product of carbon dioxide in your brain …or inhaling and holding too much oxygen that results in oxidative stress and kills your neurons.

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